This quantity gives a direct measure of irreversible processes. In a compact form In its general form. The first term on the second member expresses the heat flow outside the cell, while the second one results from the exchange of matter with the intercellular environment. In order to find the heat and mass flow appearing in the expression of the RIEDP given in equations 1 and 2 , we employ the well-known heat and mass transport equations.
We consider a rectangular frame xyz with the origin in the center of the cell and we suppose that the flow direction is along x see Fig. Concerning the heat diffusion, it is mainly due to a conduction transport neglecting the convection transport present to a much lesser extent inside a typical cell and the term of heat source.
Hence, it is. We are grateful to S. Gangi, A. Strazzanti and F.
Introduction to Thermodynamics of Irreversible Processes, Ilya Prigogine
Borziani for helpful discussion and kind support in this research activity. We thank Domenico Romolo for his graphical support in making Fig. This work is dedicated to the memory of Ilya Prigogine in occasion of his th birth anniversary. All authors contributed to the analysis of the results. Electronic supplementary material. Supplementary information accompanies this paper at doi Publisher's note: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
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Introduction to Thermodynamics of Irreversible Processes - PDF Free Download
Published online Aug Zivieri , 1, 2 N. Pacini , 3 G. Finocchio , 2 and M. Carpentieri 4. Citelli 6, Catania, Italy Find articles by N. Author information Article notes Copyright and License information Disclaimer. Zivieri, Email: ti. Corresponding author. Received Mar 30; Accepted Jul This article has been cited by other articles in PMC. Abstract In living systems, it is crucial to study the exchange of entropy that plays a fundamental role in the understanding of irreversible chemical reactions.
Introduction The irreversible processes in living systems are fundamental for determining the autopoietic life development and lead to entropy production in living systems 1 — 3. Model for the calculation of the rate of entropy in living systems We have studied the cell as an open thermodynamic system in local equilibrium. Application of the rate of entropy model to glucose catabolism in normal and cancer breast cells We have applied the general model, described in the previous section, to glucose catabolism in a typical epithelial breast tissue.
Open in a separate window. Figure 1. Figure 2. Table 1 Chemical potentials and diffusion coefficients for the chemical species involved in glucose catabolism for cell respiration and lactic acid fermentation. Figure 3. Discussion According to the described model, we can draw important conclusions about the cell behaviour during glucose catabolism in terms of entropy production. Methods Basic principles Let us consider an open system cell that exchanges energy and matter with the environment. Diffusion equations In order to find the heat and mass flow appearing in the expression of the RIEDP given in equations 1 and 2 , we employ the well-known heat and mass transport equations.
Electronic supplementary material Supplementary Information 1. Author Contributions R. Notes Competing Interests The authors declare that they have no competing interests. Footnotes Electronic supplementary material Supplementary information accompanies this paper at doi References 1. Microscopic theory of irreversible processes. Lucia U. Phenomenological theory of ontogenesis. Luisi PL.
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The minimal autopoietic unit. Life Evol. Non-enzymatic glycolysis and pentose phosphate pathway-like reactions in a plausible Archean ocean. Nicolis, G. Self-organization in non-equilibrium systems Wiley, Clausius, R. The Mechanical Theory of Heat. London Taylor and Francis, Huang, K. Statistical mechanics Wiley, Interplay between epigenetics and metabolism in oncogenesis: mechanisms and therapeutic approaches.
Peng M, et al. Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism. Moussaieff A, et al. Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells. Cell Metab. Gut P, Verdin E. The nexus of chromatin regulation and intermediary metabolism.
Metabolism-epigenome crosstalk in physiology and diseases. Banerji CR, et al. Himeoka Y, Kaneko K. Entropy production of a steady-growth cell with catalytic reactions. Vilar JMG. Entropy, Ergodicity, and Stem Cell Multipotency. Network transfer entropy and metric space for causality inference. Work fluctuation and total entropy production in nonequilibrium processes. Warburg O. On respiratory impairment in cancer cells. Pacini N, Borziani F. Cancer stem cell theory and the warburg effect, two sides of the same coin? Cancer stem-like cells can be induced through dedifferentiation under hypoxic conditions in glioma, hepatoma and lung cancer.
Cell Death Dis. ATP citrate lyase expression is associated with advanced stage and prognosis in gastric adenocarcinoma. Li, X. Metabolic reprogramming is associated with flavopiridol resistance in prostate cancer DU cells. Metabolic reprogramming: a hallmark of viral oncogenesis. Baumann K. Stem cells: A metabolic switch. Cell Biol. Ito K, Suda T. Metabolic requirements for the maintenance of self-renewing stem cells.
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Marinelli B, et al. Grootjans W, et al. Wulaningsih W, et al. Serum lactate dehydrogenase and survival following cancer diagnosis. Lucia U, Grisolia G. Second law efficiency for living cells. Deviation of the living system from the stationary state during oogenesis. Wilhelm Roux Archiv. Carnot efficiency: Why? Physica A.
Electromagnetic waves and living cells: A kinetic thermodynamic approach. Daniele S, et al. Lactate dehydrogenase-A inhibition induces human glioblastoma multiforme stem cell differentiation and death. Son MJ, et al. Hallmarks of cancer stem cell metabolism. Scott, C. Lucia U, et al. Constructal thermodynamics combined with infrared experiments to evaluate temperature differences in cells.
Okabe C, et al.
What is a Reversible Process?
Intracellular temperature mapping with a fluorescent polymeric thermometer and fluorescence lifetime imaging microscopy. Kase K, Hahn GM. Differential heat response of normal and transformed human cells in tissue culture. Ohtake M. Hyperthermia and chemotherapy using Fe Salen nanoparticles might impact glioblastoma treatment. Kondepudi, D. Modern thermodynamics: From heat engines to dissipative structures Wiley, Dabbs DJ, et al.
Prigogine, I. Far to be limited to students having to learn the subject, this impression is sometimes mentioned by specialists themselves who confess not being totally sure of the consistency of the thermodynamic theory, despite the fact that its practical usefulness is indisputable. The present paper deals with this interesting question and leads to the idea that there is an imperfect convergence between the way of using the thermodynamic tool and the way of understanding its significance.
Illustrated by a very simple example, the discussion can be followed by every scientist having the fundamental basis in thermodynamics. The suggested hypothesis is that the Einstein mass-energy relation is closely associated to the concept of entropy, opening a link between thermodynamics and relativity. Related Articles:. Date: March 24, Date: July 29, Code Switching in Sons and Lovers.